Biological properties of exopolysaccharides produced by Bacillus spp

Microbiol Res. 2023 Mar:268:127276. doi: 10.1016/j.micres.2022.127276. Epub 2022 Dec 5.

Abstract

There is currently a constant search for ecofriendly bioproducts, which could contribute to various biomedical applications. Among bioproducts, exopolysaccharides are prominent contemporary extracellular biopolymers that are produced by a great variety of bacterial species. These homo- or heteropolymers are composed of monomeric sugar units linked by glycosidic bonds, which are secreted to the external medium. Bacillus spp. are reported to be present in different ecosystems and produce exopolysaccharides with different biological properties such as antioxidant, antibacterial, antiviral anti-inflammatory, among others. Since a great diversity of bacterial strains are able to produce exopolysaccharides, a great variation in the molecular composition is observed, which is indeed present in some of the chemical structures predicted until date. These molecular characteristics and their relations with different biological functions are discussed in order to visualize future applications in biomedical section.

Keywords: Anti-inflammatory; Antimicrobial; Antioxidant; Antiviral; Biomedicine.

Publication types

  • Review

MeSH terms

  • Antiviral Agents
  • Bacillus*
  • Bacteria
  • Ecosystem
  • Polysaccharides, Bacterial / chemistry

Substances

  • Polysaccharides, Bacterial
  • Antiviral Agents