Rapid bacterial identification from formalin-fixed paraffin-embedded neuropathology specimens using 16S rDNA nanopore sequencing

Neuropathol Appl Neurobiol. 2023 Feb;49(1):e12871. doi: 10.1111/nan.12871.

Authors

Anne Albers¹, Dorothee Cäcilia Spille², Eric Suero-Molina², Frieder Schaumburg³, Walter Stummer², Werner Paulus¹, Christian Thomas¹

Affiliations

¹ Institute of Neuropathology, University Hospital Münster, Münster, Germany.
² Department of Neurosurgery, University Hospital Münster, Münster, Germany.
³ Institute of Medical Microbiology, University Hospital Münster, Münster, Germany.

PMID: 36534112
DOI: 10.1111/nan.12871

No abstract available

Keywords: bacterial; brain abscess; infection; metagenomics; molecular diagnostics; nanopore sequencing.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

DNA, Ribosomal
Formaldehyde
Humans
Nanopore Sequencing*
Nervous System Diseases*
Paraffin Embedding
Sequence Analysis, DNA

Substances

DNA, Ribosomal
Formaldehyde