Structure, Biodegradation, and In Vitro Bioactivity of Zn-1%Mg Alloy Strengthened by High-Pressure Torsion

Natalia Martynenko; Natalia Anisimova; Olga Rybalchenko; Mikhail Kiselevskiy; Georgy Rybalchenko; Natalia Tabachkova; Mark Zheleznyi; Diana Temralieva; Viacheslav Bazhenov; Andrey Koltygin; Andrey Sannikov; Sergey Dobatkin

doi:10.3390/ma15249073

Structure, Biodegradation, and In Vitro Bioactivity of Zn-1%Mg Alloy Strengthened by High-Pressure Torsion

Materials (Basel). 2022 Dec 19;15(24):9073. doi: 10.3390/ma15249073.

Authors

Natalia Martynenko¹, Natalia Anisimova^{1

2

3}, Olga Rybalchenko¹, Mikhail Kiselevskiy^{2

3}, Georgy Rybalchenko⁴, Natalia Tabachkova^{5

6}, Mark Zheleznyi^{1

6

7}, Diana Temralieva¹, Viacheslav Bazhenov⁸, Andrey Koltygin⁸, Andrey Sannikov^{1

8}, Sergey Dobatkin^{1

9}

Affiliations

¹ A.A. Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences, Leninskiy Prospect, 49, 119334 Moscow, Russia.
² Center for Biomedical Engineering, National University of Science and Technology "MISIS", 119049 Moscow, Russia.
³ N.N. Blokhin National Medical Research Center of Oncology (N.N. Blokhin NMRCO) of the Ministry of Health of the Russian Federation, 115478 Moscow, Russia.
⁴ P.N. Lebedev Physical Institute of the Russian Academy of Sciences, 119991 Moscow, Russia.
⁵ A.M. Prokhorov General Physics Institute of the Russian Academy of Sciences, 119991 Moscow, Russia.
⁶ Department of Physical Materials Science, National University of Science and Technology "MISIS", 119049 Moscow, Russia.
⁷ Institute of Innovative Engineering Technologies, Peoples' Friendship University of Russia (RUDN University), 117198 Moscow, Russia.
⁸ Casting Department, National University of Science and Technology "MISIS", 119049 Moscow, Russia.
⁹ Department of Metal Science and Physics of Strength, National University of Science and Technology "MISIS", 119049 Moscow, Russia.

Abstract

The effect of high-pressure torsion (HPT) on the microstructure, phase composition, mechanical characteristics, degradation rate, and bioactive properties of the Zn-1%Mg alloy is studied. An ultrafine-grained (UFG) structure with an average grain size of α-Zn equal to 890 ± 26 nm and grains and subgrains of the Mg₂Zn₁₁ and MgZn₂ phases with a size of 50-100 nm are formed after HPT. This UFG structure leads to an increase in the ultimate tensile strength of the alloy by ~3 times with an increase in elongation to 6.3 ± 3.3% due to the formation of a basal texture. The study of corrosion resistance did not show a significant effect of HPT on the degradation rate of the alloy. In addition, no significant changes in the bioactivity of the alloy after HPT: hemolysis, cellular colonization and Escherichia coli growth inhibition.

Keywords: bioactivity; degradation; ductility; hemolysis; high pressure torsion (HPT); microstructure; phase composition; strength; zinc alloys.

Grants and funding

22-23-00097/Russian Science Foundation