Transient Global Ventricular Hypertrophy in a Patient With Multisystem Inflammatory Syndrome in Children (MIS-C) Correlated With High-Dose Glucocorticoid Treatment: A Case Report

Zachary E West; Matthew Dove; Lazaros K Kochilas; Matthew E Oster

doi:10.7759/cureus.32139

Transient Global Ventricular Hypertrophy in a Patient With Multisystem Inflammatory Syndrome in Children (MIS-C) Correlated With High-Dose Glucocorticoid Treatment: A Case Report

Cureus. 2022 Dec 2;14(12):e32139. doi: 10.7759/cureus.32139. eCollection 2022 Dec.

Authors

Zachary E West^{1

2}, Matthew Dove^{1

2}, Lazaros K Kochilas^{1

2}, Matthew E Oster^{1

2}

Affiliations

¹ Department of Pediatrics, Emory University School of Medicine, Atlanta, USA.
² Division of Pediatric Cardiology, Children's Healthcare of Atlanta, Atlanta, USA.

Abstract

Multisystem inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection has been shown to lead to depressed cardiac function. Standard treatment includes high-dose glucocorticoids (GC). We present the unusual case of a teenager who developed transient echocardiographic global ventricular hypertrophy following GC administration during his treatment for MIS-C, with the resolution of the hypertrophy after cessation of GC.

Keywords: covid; covid 19; glucocorticoids; mis-c; multisystem inflammatory syndrome in children; transient ventricular hypertrophy.

Publication types

Case Reports