First case of subcutaneous cystic phaeohyphomycosis due to Phialophora chinensis in a kidney transplant recipient in Martinique

Clément Pruvot; Anne Laure Messagier; Dea Garcia-Hermoso; Fréderic Lebailly; Cédric Aglae; Nicole Desbois-Nogard

doi:10.1016/j.mmcr.2022.12.003

First case of subcutaneous cystic phaeohyphomycosis due to Phialophora chinensis in a kidney transplant recipient in Martinique

Med Mycol Case Rep. 2022 Dec 25:39:18-22. doi: 10.1016/j.mmcr.2022.12.003. eCollection 2023 Mar.

Authors

Clément Pruvot¹, Anne Laure Messagier¹, Dea Garcia-Hermoso², Fréderic Lebailly³, Cédric Aglae⁴, Nicole Desbois-Nogard⁵

Affiliations

¹ Dermatology Department, Pierre-Zobda-Quitman Hospital, CHU Martinique, BP 636, 927261, Fort de France, cedex, Martinique.
² Institut Pasteur, Université Paris Cité, CNRS UMR2000, Unité de Mycologie Moléculaire, F-75015, Paris, France.
³ Orthopedic Surgery Department, Clinique Saint-Paul, 97200, Fort de France, Martinique.
⁴ Department of Nephrology, CHU Martinique, BP 636, 927261, Fort de France, cedex, Martinique.
⁵ Parasitology-Mycology Laboratory, Pierre-Zobda-Quitman Hospital, CHU Martinique, BP 636, 927261, Fort de France, cedex, Martinique.

Abstract

We report a case of subcutaneous mycosis in the form of a subcutaneous cyst of the index finger, successfully treated by surgery and posaconazole in an 84-year-old female kidney transplant patient. Intra-operative mycological analysis enabled the diagnosis of Phialophora chinensis phaeohyphomycosis. Phialophora chinensis is an environmental mold recently described in human pathology in cases of chromoblastomycosis. This is the first case of subcutaneous phaeohyphomycosis due to Phialophora chinensis in an immunocompromised patient.

Keywords: Immunosuppression; Kidney transplant; Martinique; Phaeohyphomycosis; Phialophora chinensis; Subcutaneous cyst.

Publication types

Case Reports