Reduced circulating BMP9 and pBMP10 in hospitalized COVID-19 patients

Pulm Circ. 2023 Jan 1;13(1):e12192. doi: 10.1002/pul2.12192. eCollection 2023 Jan.

Abstract

Similar to other causes of acute respiratory distress syndrome, coronavirus disease 2019 (COVID-19) is characterized by the aberrant expression of vascular injury biomarkers. We present the first report that circulating plasma bone morphogenetic proteins (BMPs), BMP9 and pBMP10, involved in vascular protection, are reduced in hospitalized patients with COVID-19.

Keywords: BMPs; endothelial cell dysfunction; viral infections and pathogenesis.