Role of hypertension in progression of pediatric CKD

Pediatr Nephrol. 2023 Nov;38(11):3519-3528. doi: 10.1007/s00467-023-05894-1. Epub 2023 Feb 3.

Abstract

Hypertension is frequent in children with chronic kidney disease (CKD). Its prevalence varies according to CKD stage and cause. It is relatively uncommon in children with congenital kidney disease, while acquired kidney disease is associated with a higher prevalence of hypertension. Studies in children with CKD utilizing ambulatory blood pressure monitoring also showed a high prevalence of masked hypertension. Uncontrolled and longstanding hypertension in children is associated with progression of CKD. Aggressive treatment of high blood pressure should be an essential part of care to delay CKD progression in children.

Keywords: Blood pressure; Children; Chronic kidney disease; Hypertension; Progression; Treatment.

Publication types

  • Review

MeSH terms

  • Blood Pressure / physiology
  • Blood Pressure Monitoring, Ambulatory
  • Child
  • Humans
  • Hypertension* / complications
  • Hypertension* / diagnosis
  • Hypertension* / epidemiology
  • Renal Insufficiency, Chronic* / complications
  • Renal Insufficiency, Chronic* / epidemiology
  • Risk Factors