Omadacycline for the treatment of Mycobacterium abscessus infections: Case series and review of the literature

Ayesha Siddiqa; Shanza Khan; George D Rodriguez; Carl Urban; Sorana Segal-Maurer; Glenn Turett

doi:10.1016/j.idcr.2023.e01703

Omadacycline for the treatment of Mycobacterium abscessus infections: Case series and review of the literature

IDCases. 2023 Jan 20:31:e01703. doi: 10.1016/j.idcr.2023.e01703. eCollection 2023.

Authors

Ayesha Siddiqa^{1

2}, Shanza Khan^{1

2}, George D Rodriguez^{1

3

4}, Carl Urban^{1

2

5}, Sorana Segal-Maurer^{1

2

5}, Glenn Turett^{1

2}

Affiliations

¹ Department of Medicine, NewYork-Presbyterian Queens, 56-45 Main St., Flushing, NY 11355, United States of America.
² The Dr. James J. Rahal, Jr. Division of Infectious Diseases, NewYork-Presbyterian Queens, 56-45 Main St., Flushing, NY 11355, United States of America.
³ Division of Antimicrobial Stewardship, NewYork-Presbyterian Queens, 56-45 Main St., Flushing, NY 11355, United States of America.
⁴ Columbia University School of Nursing, Columbia University, NY 10032, United States of America.
⁵ Weill Cornell Medical College, Cornell University, NY 10065, United States of America.

Abstract

Treatment of Mycobacterium abscessus infections are problematic due to inherent multidrug resistance and lack of response to antibacterials commonly used as therapy for other mycobacterial infections. We report the clinical success of five patients who received definitive-treatment with an omadacycline-containing combination regimen for M. abscessus infection.

Keywords: Mycobacterium abscessus; Omadacycline; Synergy; Therapy.

Publication types

Case Reports