Patterns of Medication Management and Associated Medical and Clinical Features among Home-Dwelling Older Adults: A Cross-Sectional Study in Central Portugal

Int J Environ Res Public Health. 2023 Jan 17;20(3):1701. doi: 10.3390/ijerph20031701.

Abstract

Ageing is frequently associated with multimorbidity and polypharmacy. The present study aimed to identify the current medication management patterns and the profiles of home-dwelling older adults and to find any association with their conditions, including frailty and cognitive impairment. Within the scope of this cross-sectional study, 112 older adults living in the community were assessed via face-to-face structured interviews. Frailty, cognitive status, medication management and clinical and sociodemographic variables were evaluated. Descriptive and inferential statistics were calculated. The mean participant age was 76.6 ± 7.1 years, 53.6% of participants were women, and 40.2% of participants lived alone. More than half were classified as having frailty (58.9%), almost one-fifth (19.6%) presented with a moderate cognitive impairment had more than one disease, and 60.7% were polymedicated. No associations were found between polymedication and medication self-management, the use of over-the-counter medications, living alone, having a poor understanding of pharmacological therapy and/or pathology, or having more than one prescriber. Self-management was associated with age, the number of medications, frailty and cognitive status. Binary logistic regressions showed that cognitive impairment had statistically significant differences with medication management, having a poor understanding of pharmacological therapy and/or pathology, having one prescriber and the use of medications not prescribed by physicians. Interventions to prevent medication-related problems in home-dwelling older adults are recommended.

Keywords: frailty; home-dwelling; medication management; medication-related problems; multimorbidity; older adults; polypharmacy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cognitive Dysfunction* / epidemiology
  • Cross-Sectional Studies
  • Female
  • Frailty* / epidemiology
  • Humans
  • Independent Living
  • Male
  • Medication Therapy Management
  • Portugal / epidemiology

Grants and funding

This research is funded by the Joint Swiss–Portuguese academic programme from the University of Applied Sciences and Arts Western Switzerland (HES-SO) and the Foundation for Science and Technology (FCT), grant number 105 995. S.G.P. is funded by Fundação para a Ciência e Tecnologia (FCT) (CEECINST/00051/2018). M.d.A.D., J.P. and S.G.P. also acknowledge FCT funding for ciTechCare (UIDB/05704/2020).