Severe Acute Respiratory Syndrome Coronavirus-2 Lambda Variant Collected from a Child from Arkansas and Sequenced

Lori Wong; Christopher Randolph; Emily Kanwischer; Ashton Ingold; Bobby L Boyanton Jr; Jay Taylor; Rachel A Frenner; Susan E Harley; Jordan T Bird; Timothy J Thurman; Sangam Kandel; David W Ussery; Stephanie D Byrum; Darrell Dinwiddie; Daryl Domman; Uday K Chalwadi; Joshua Kennedy

doi:10.1128/mra.00007-23

Severe Acute Respiratory Syndrome Coronavirus-2 Lambda Variant Collected from a Child from Arkansas and Sequenced

Microbiol Resour Announc. 2023 Mar 16;12(3):e0000723. doi: 10.1128/mra.00007-23. Epub 2023 Feb 13.

Authors

Lori Wong¹, Christopher Randolph^{2

3}, Emily Kanwischer³, Ashton Ingold³, Bobby L Boyanton Jr^{4

5}, Jay Taylor⁵, Rachel A Frenner⁵, Susan E Harley⁴, Jordan T Bird², Timothy J Thurman², Sangam Kandel¹, David W Ussery¹, Stephanie D Byrum^{2

3}, Darrell Dinwiddie⁶, Daryl Domman⁷, Uday K Chalwadi⁸, Joshua Kennedy^{3

8

9}

Affiliations

¹ Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
² Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
³ Arkansas Children's Research Institute, Little Rock, Arkansas, USA.
⁴ Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
⁵ Department of Pathology, Arkansas Children's Hospital, Little Rock, Arkansas, USA.
⁶ Department of Pediatrics, University of New Mexico, Albuquerque, New Mexico, USA.
⁷ Center for Global Health, Dept of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.
⁸ Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
⁹ Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Abstract

An eleven-year-old tested positive for SARS-CoV-2 Lambda variant. Sequencing was performed on the Oxford Nanopore and the Illumina NextSeq 500. Both platforms identified all 7 of the synonymous mutations in the sample, while all 28 nonsynonymous mutations were identified from Oxford Nanopore and 20 nonsynonymous mutations were identified from Illumina.

Abstract

Grants and funding