Cerebellar haemorrhage triggered by allergic reaction to maintenance haemodialysis in a patient with eosinophilia

BMJ Case Rep. 2023 Feb 14;16(2):e254126. doi: 10.1136/bcr-2022-254126.

Abstract

We report a case of eosinophilia and an allergic reaction that caused a cerebellar haemorrhage.An woman in her 80s presented with headache, dyspnoea and vomiting with severe hypotension soon after switching the dialysis membrane, and a CT scan revealed cerebellar haemorrhage. In the subsequent clinical course, the patient developed an allergic reaction to multiple membranes and required corticosteroids to continue haemodialysis (HD). Pre-existing eosinophilia is a risk factor for cerebral infarctions and dialysis membrane allergy, which is a common feature in patients undergoing HD. Membrane switching and corticosteroid therapy must be considered in case of multiple membrane allergies.

Keywords: Allergy, asthma; Chronic renal failure; Dialysis; Stroke.

Publication types

  • Case Reports

MeSH terms

  • Eosinophilia* / etiology
  • Female
  • Hemorrhage / complications
  • Humans
  • Hypersensitivity* / complications
  • Kidney Failure, Chronic* / therapy
  • Renal Dialysis / adverse effects