It takes a sec(22b) to accrue plasma cells

Immunol Cell Biol. 2023 Apr;101(4):285-288. doi: 10.1111/imcb.12629. Epub 2023 Feb 28.

Abstract

A recent study shows that the SNARE protein Sec22b plays a key role in antibody-secreting plasma cell accrual. Without Sec22b, antibody titres were diminished, and plasma cells rare to undetectable. The few plasma cells that were detected were functionally compromised, with altered organelle morphology and deficient antibody production.

Publication types

  • Comment

MeSH terms

  • Plasma Cells* / metabolism
  • R-SNARE Proteins / metabolism

Substances

  • R-SNARE Proteins