Gastric hypoacidity as a risk factor for gastric and other cancers

IARC Sci Publ. 1987:(84):524-6.

Abstract

Evidence is presented and discussed to test the hypothesis that the excess risk of gastric cancer observed in patients with decreased gastric acidity is caused by metabolites of nitrite, possibly N-nitroso compounds.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Achlorhydria / etiology
  • Achlorhydria / metabolism*
  • Anemia, Pernicious / complications
  • Gastrectomy
  • Gastric Juice / analysis*
  • Gastric Juice / microbiology
  • Humans
  • Nitrates / metabolism
  • Nitrites / metabolism
  • Peptic Ulcer / complications
  • Postoperative Complications / metabolism
  • Risk Factors
  • Stomach Neoplasms / etiology*
  • Stomach Neoplasms / mortality

Substances

  • Nitrates
  • Nitrites