Incidence of Brain Metastases and Preliminary Evidence of Intracranial Activity With Sotorasib in Patients With KRAS^G12C-Mutant Non-Small-Cell Lung Cancer

JCO Precis Oncol. 2023 Feb:7:e2200621. doi: 10.1200/PO.22.00621.

Authors

Giuseppe Lamberti¹, Ayal Aizer², Biagio Ricciuti¹, Joao V Alessi¹, Federica Pecci¹, Shu-Chi Tseng^{3

4}, Lynette M Sholl⁵, Mizuki Nishino³, Mark M Awad¹

Affiliations

¹ Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.
² Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, MA.
³ Department of Radiology, Brigham and Women's Hospital, Boston, MA.
⁴ Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Chang Gung University, Taoyuan, Taiwan.
⁵ Department of Pathology, Brigham and Women's Hospital, Boston, MA.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Brain Neoplasms*
Carcinoma, Non-Small-Cell Lung*
Humans
Incidence
Lung Neoplasms*
Proto-Oncogene Proteins p21(ras)

Substances

sotorasib
Proto-Oncogene Proteins p21(ras)
KRAS protein, human