[Lymphocytic "…itis", from esophagus to large bowel]

Ann Pathol. 2023 Jun;43(3):266-279. doi: 10.1016/j.annpat.2023.01.010. Epub 2023 Feb 23.
[Article in French]

Abstract

Intra-epithelial lymphocytosis is an elementary lesion frequently observed in the gastrointestinal tract, which can be found from the esophagus to the colon. Many conditions of a varied nature (dysimmunitary diseases, drugs, infections…) are associated with intra-epithelial lymphocytosis, and the etiological diagnosis most often requires an anatomo-clinical correlation. The pathologist will have to identify histological lesions associated with intra-epithelial lymphocytosis allowing the diagnosis to be oriented in order to propose appropriate treatment. In this review, the main entities associated with digestive intra-epithelial lymphocytosis will be presented, detailing the key elements allowing their diagnosis.

Keywords: Colite lymphocytaire; Duodénite lymphocytaire; Gastrite lymphocytaire; Intra-epithelial; Intra-épithélial; Lymphocytic colitis; Lymphocytic duodenitis; Lymphocytic esophagitis; Lymphocytic gastritis; Lymphocytose; Lymphocytosis; Œsophagite lymphocytaire.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Celiac Disease* / complications
  • Celiac Disease* / pathology
  • Colon / pathology
  • Esophagus / pathology
  • Humans
  • Lymphocytes / pathology
  • Lymphocytosis* / complications
  • Lymphocytosis* / etiology