Women Living with HIV in Italian Prison Settings: Results from the Gender-Specific ROSE Network

Viruses. 2023 Feb 10;15(2):497. doi: 10.3390/v15020497.

Abstract

Background: Incarcerated women are a minority in the Italian prison population. The lack of prevention and awareness of HIV infection and the lack of access to treatment make the treatment path difficult.

Methods: we conducted a multi-center study including incarcerated women living with HIV (WLWH).

Results: The study included 85 WLWH with a mean age of 41.7 ± 8.7 years, and 58.8% (50/85) of them were Italian. Principally, HIV transmission was related to sexual intercourse, 47% of all patients were PWIDs, and 62.5% of them were on opioid substitution therapy (OST). Overall, 56.4% of the included patients had a CD4+ cell count of >500 cells/mmc. Among the participants, 92.9% were on antiretroviral therapy, 87.3% had treatment before incarceration, and 83.5% were virologically suppressed. Among the 13 non-virally-suppressed patients, 53.8% were unaware of their serological status before incarceration and had started HAART but were still not virologically suppressed; 46.2% (6/13) had a lack of compliance or had suspended the treatment before incarceration and restarted it after admission. All patients with chronic hepatitis C underwent treatment with direct-acting antivirals and reached a sustained virological response.

Conclusions: the detention of these women could represent an occasion for the patients' healthcare provision and use, and the creation of a gender-specific network can be an effective strategy for reaching this population.

Keywords: HBV; HCV; HIV; health disparities; prison settings.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Antiretroviral Therapy, Highly Active
  • Antiviral Agents
  • Female
  • HIV Infections* / drug therapy
  • HIV Infections* / epidemiology
  • Hepatitis C, Chronic*
  • Humans
  • Italy / epidemiology
  • Middle Aged
  • Prisons

Substances

  • Antiviral Agents

Grants and funding

This research received no external funding.