Postamputation diagnosis of squamous cell carcinoma in a patient with lymphedema

J Vasc Surg Cases Innov Tech. 2023 Jan 14;9(1):101100. doi: 10.1016/j.jvscit.2023.101100. eCollection 2023 Mar.

Abstract

Chronic lymphedema is fraught with morbidity, including tissue loss. We present the case of a woman with long-standing lymphedema suffering from nonhealing ulcerations despite multiple interventions, who underwent below-knee amputation. Surgical pathology yielded a diagnosis of invasive squamous cell carcinoma. We highlight the uncommon association between lymphedema and squamous cell carcinoma, and the importance of routine pathological testing with lower extremity amputations.

Keywords: Amputation; Chronic lymphedema; Squamous cell carcinoma.

Publication types

  • Case Reports