Not so uncommon, yet neglected 'Severe Streptococcus pyogenes infections at a tertiary care center in south India

Indian J Med Microbiol. 2023 Jan-Feb:41:55-58. doi: 10.1016/j.ijmmb.2022.12.006. Epub 2023 Jan 11.

Abstract

Streptococcus pyogenes (SP) causes uncomplicated infections of throat & skin to severe life-threatening invasive diseases and poststreptococcal sequelae. Despite being common, it hasn't been studied much in recent times. Data of 93 adult patients >18 years, culture proven (SP) infections from 2016 to 2019 was studied in south India. Irrespective of comorbidities, SSTI were most common followed by surgical site infections& bacteremia. Isolates were susceptible to penicillin, cephalosporins but 23% were resistant to clindamycin. Timely surgical interventions and appropriate antibiotics reduced morbidity& limb salvage by 9 times. Larger studies, worldwide, to see the current trend of SP need to be conducted.

Keywords: Clindamycin; Group A streptococcus; Necrotising fascitis; Skin and soft tissue infection; Streptococcus pyogenes.

MeSH terms

  • Adult
  • Clindamycin
  • Humans
  • India
  • Streptococcal Infections*
  • Streptococcus pyogenes*
  • Tertiary Care Centers

Substances

  • Clindamycin