Granulomatous anterior uveitis following mRNA-based COVID-19 vaccination: A case report

Indian J Ophthalmol. 2023 Mar;71(3):1033-1035. doi: 10.4103/ijo.IJO_1771_22.

Abstract

A 23-year-old patient presented with complaints of redness, pain, photophobia, and blurred vision in the right eye 15 days after she received the third dose of BNT162b2 vaccination. Ocular examination revealed 2+ cellular reactions in the anterior chamber and mutton fat keratic precipitate with no vitritis or retinal alterations. Active uveitis findings regressed with corticosteroid and cycloplegic eye drops. We present a case of unilateral granulomatous anterior uveitis following the BNT162b2 vaccination, with no etiologic factor in uveitis work-up and no previous history of uveitis before vaccination. This report demonstrates a potential causal association of coronavirus disease 2019 (COVID-19) vaccine with granulomatous anterior uveitis.

Keywords: BNT162b2; COVID-19; COVID-19 vaccine; granulomatous anterior uveitis; mutton fat keratic precipitate.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Anterior Chamber
  • BNT162 Vaccine
  • COVID-19 Vaccines
  • COVID-19*
  • Female
  • Humans
  • Uveitis*
  • Uveitis, Anterior*
  • Young Adult

Substances

  • COVID-19 Vaccines
  • BNT162 Vaccine