Evidence of Mpox Virus Infection Among Persons Without Characteristic Lesions or Rash Presenting for First Dose of JYNNEOS Vaccine-District of Columbia, August 2022

Yasmin P Ogale; Nicolle Baird; Michael B Townsend; Isha Berry; Isabel Griffin; Michelle Lee; Patrick Ashley; Trevor Rhodes; Tiffany Notigan; Nhien Wynn; Chantal Kling; Todd Smith; Lalita Priyamvada; William C Carson; Terese Navarra; Patrick Dawson; Paul J Weidle; Christina Willut; Anil T Mangla; Panayampalli S Satheshkumar; Christina L Hutson; David A Jackson; Michelle A Waltenburg; DC Mpox Response Project Team

doi:10.1093/cid/ciad145

Evidence of Mpox Virus Infection Among Persons Without Characteristic Lesions or Rash Presenting for First Dose of JYNNEOS Vaccine-District of Columbia, August 2022

Clin Infect Dis. 2023 Jul 26;77(2):298-302. doi: 10.1093/cid/ciad145.

Authors

Yasmin P Ogale^{1

2}, Nicolle Baird^{1

3}, Michael B Townsend¹, Isha Berry^{1

2}, Isabel Griffin^{1

2}, Michelle Lee⁴, Patrick Ashley⁴, Trevor Rhodes⁴, Tiffany Notigan⁴, Nhien Wynn¹, Chantal Kling¹, Todd Smith¹, Lalita Priyamvada¹, William C Carson¹, Terese Navarra¹, Patrick Dawson¹, Paul J Weidle¹, Christina Willut⁴, Anil T Mangla⁴, Panayampalli S Satheshkumar¹, Christina L Hutson¹, David A Jackson¹, Michelle A Waltenburg¹; DC Mpox Response Project Team

Collaborators

DC Mpox Response Project Team:
Ausaf Ahmad, Jaia Armstrong, Marie Brake, Paige Bunkley, Perri Callaway, Ayan K Chakrabarti, Jennifer Folster, Catalina Forero, Bruce Bryce Furness, Claire Godino, Lauren Greenberg, Sarah Anne J Guagliardo, Samadhan Jadhao, Teskisha Jordan, Emiko Kamitani, Barbara Keino, Erik Kopping, Joo Lee, Leah Lopez, David Lowe, John Metz, Shanna Miko, Victoria Mrotz, Adi Noiman, James Partin, Melissa Brykailo Pearce, Kevin Pettus, Sergio Rodriguez, Susanna Sabin, Loredana Santo, Caroline A Schrodt, Pankaj Sharma, Victoria Shelus, Dallas Shi, Olutomi Sodeke, Nora Springstubb, Christan Halverson Stager, Roxana Rodriguez Stewart, Xiaoling Tang, Moukaram Tertuliano, Logan Timm, Casey Vantucci, Gilberto Vaughan, Sarah Wondmeneh, Yong Yang, Eric Anthony, Marie Argyriou, Leslie Ayuk-Takor, Miriam Bryant, Angela Cherrix, David Coleman, Carole Cunningham, Ronit Dastidar, Olivia Dato, Azam Elnour, Sarah Gillani, Tracie Hartley, Dionnie Israel, Michelle Lee, Susan McCullam, Ie Meh, Tiffany Notigan, Saumya Rajamohan, Trevor Rhodes, Blanca Rosado, Julia Rowse, Brandon Shapiro, Kristen Smart, Michael Staff, Jaketia Taylor, Ricardo Webb, Rajanique White, Saria Widatalla, Shanice Wilson

Affiliations

¹ Centers for Disease Control and Prevention, Multinational Mpox Response, Atlanta, GA, USA.
² Epidemic Intelligence Service, Center for Surveillance, Epidemiology and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
³ Laboratory Leadership Service, Center for Surveillance, Epidemiology and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
⁴ DC Health, Washington, DC, USA.

PMID: 36916132
DOI: 10.1093/cid/ciad145

Abstract

We assessed mpox virus prevalence in blood, pharyngeal, and rectal specimens among persons without characteristic rash presenting for JYNNEOS vaccine. Our data indicate that the utility of risk-based screening for mpox in persons without skin lesions or rash via pharyngeal swabs, rectal swabs, and/or blood is likely limited.

Keywords: asymptomatic; mpox; pharyngeal swab; rectal swab.

Published by Oxford University Press on behalf of Infectious Diseases Society of America 2023.

MeSH terms

District of Columbia
Exanthema* / etiology
Humans
Mpox (monkeypox)*
Vaccines, Attenuated
Virus Diseases*

Substances

smallpox and monkeypox vaccine modified vaccinia ankara-bavarian nordic
Vaccines, Attenuated