A novel mutation (p.Y24N) in NHP2 leads to idiopathic pulmonary fibrosis and lung carcinoma chronic obstructive lung disease by disrupting the expression and nucleocytoplasmic localization of NHP2

Biochim Biophys Acta Mol Basis Dis. 2023 Jun;1869(5):166692. doi: 10.1016/j.bbadis.2023.166692. Epub 2023 Mar 16.

¹ Department of Pulmonary and Critical Care Medicine, Research Unit of Respiratory Disease, Hunan Diagnosis and Treatment Center of Respiratory Disease, the Second Xiangya Hospital, Central South University, Changsha, China.
² Department of Cell Biology, School of Life Science, Central South University, Changsha, China.
³ Department of Pulmonary and Critical Care Medicine, Research Unit of Respiratory Disease, Hunan Diagnosis and Treatment Center of Respiratory Disease, the Second Xiangya Hospital, Central South University, Changsha, China. Electronic address: [email protected].
⁴ Department of Cell Biology, School of Life Science, Central South University, Changsha, China. Electronic address: [email protected].

No abstract available

Keywords: Chronic obstructive lung disease; Idiopathic pulmonary fibrosis; NHP2 mutation; Telomerase complex.

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