Case report: Type 2 diabetes mellitus with plantar malignant melanoma: Report of two cases

Bi-Ling Huang; Min Tan; Ming-Liu Li; Yuan-Yuan Teng; Min Zhou; Min Wang

doi:10.3389/fonc.2023.1089578

Case report: Type 2 diabetes mellitus with plantar malignant melanoma: Report of two cases

Front Oncol. 2023 Mar 3:13:1089578. doi: 10.3389/fonc.2023.1089578. eCollection 2023.

Authors

Bi-Ling Huang^{1

2}, Min Tan^{1

2}, Ming-Liu Li^{1

2}, Yuan-Yuan Teng^{1

2}, Min Zhou^{1

2}, Min Wang^{1

2}

Affiliations

¹ Department of Endocrinology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
² National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Abstract

Malignant melanoma is a highly malignant tumor that originates from melanocytes. It has a poor prognosis and rarely occurs on the foot. Diabetic foot ulcer is one of the most serious chronic complications of diabetes. This paper reports two cases of type 2 diabetes patients with malignant melanoma on the foot. Clinicians should improve their understanding of patients with diabetes with acral malignant melanoma. When diabetic foot ulcers occur repeatedly and continue not to heal, the clinical features of the cutaneous lesions are similar to malignant melanoma, and a pathological biopsy of the lesions should be performed promptly to obtain a clear diagnosis, avoid a missed diagnosis and improve the survival rate.

Keywords: case report; diabetic foot ulcer; malignant melanoma; plantar malignant melanoma; type 2 diabetes.

Publication types

Case Reports

Grants and funding

This work was supported by the National Natural Science Foundation (81873643,82270930), 2019 Hunan Natural Science Foundation General Project (2019JJ40517), the Foundation of Hunan Provincial Science and Technology Department(2021ZK4218), Teaching Reform Project of Hunan Province Regular Universities (HNJG-2021-0313) and Hunan Provincial Degree and Postgraduate Teaching Reform Project (2021JGYB033).