A one-pot, four-component reaction for the synthesis of novel chromeno[3,4-c]spiropyrrolidine-indenoquinoxalines is described via a 1,3-dipolar cycloaddition of 3-acetyl-coumarins with the azomethine ylides followed by deacetylation and protonation (deuteration). The products were obtained in moderate to high yields, and their structures were confirmed by 1H NMR, 13C NMR, FT-IR, and MS spectroscopy.
Keywords: 1,3-dipolar cycloaddition reaction; 3-acetyl-coumarins; azomethine ylides; one-pot reaction; spiropyrrolidine-indenoquinoxalines.
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