Laboratory perspectives in the development of polygenic risk scores for disease: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)
Genet Med. 2023 May;25(5):100804.
doi: 10.1016/j.gim.2023.100804.
Epub 2023 Mar 27.
1 Department of Pathology & Laboratory Medicine, Medical College of Wisconsin, Milwaukee, WI.
2 Division of Cardiovascular Medicine, Department of Medicine, Stanford Medicine, Stanford, CA.
3 Sema4, BioCT, Stamford, CT.
4 Bioinformatics Research and Development Laboratory, Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine, Medical College of Wisconsin, Milwaukee, WI.
5 Laboratory for Molecular Medicine, Mass General Brigham, Cambridge, MA.
6 Department of Genetics, Yale University, New Haven, CT.
7 Department of Laboratory Medicine & Pathology, UW Medicine, University of Washington, Seattle, WA.
8 Department of Genomic Medicine and Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.
9 Department of Pathology, Stanford University School of Medicine, Stanford, CA.
10 Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Utah Health, Salt Lake City, UT.
11 Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA; Harvard Medical School, Boston, MA.
12 American College of Medical Genetics and Genomics, Bethesda, MD.