A case of acute myelomonocytic leukemia morphologically mimicking lymphoblastic leukemia

Sao-Chih Ni; Chi-Yuan Yao; Feng-Ming Tien; Chien-Chin Lin

doi:10.1002/ccr3.7146

A case of acute myelomonocytic leukemia morphologically mimicking lymphoblastic leukemia

Clin Case Rep. 2023 Mar 29;11(4):e7146. doi: 10.1002/ccr3.7146. eCollection 2023 Apr.

Authors

Sao-Chih Ni¹, Chi-Yuan Yao^{1

2

3}, Feng-Ming Tien^{1

2}, Chien-Chin Lin^{1

2

3}

Affiliations

¹ Division of Hematology National Taiwan University Hospital Taipei Taiwan.
² Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan.
³ Department of Laboratory Medicine National Taiwan University Hospital Taipei Taiwan.

Abstract

We present the case of a 70-year-old man diagnosed with acute myelomonocytic leukemia, albeit that his leukemic blasts at initial presentation had scant cytoplasm, inconspicuous cytoplasmic granules, and morphologically mimicked lymphoblasts. We would like to raise the recognition that acute myelomonocytic leukemia can actually present with atypical blast morphology.

Keywords: acute lymphoblastic leukemia; acute myelomonocytic leukemia; alpha‐naphthyl butyrate esterase; flow cytometry; myeloperoxidase.

Publication types

Case Reports