Machine Learning Identifies Plasma Metabolites Associated With Heart Failure in Underrepresented Populations With the TTR V122I Variant

J Am Heart Assoc. 2023 Apr 18;12(8):e027736. doi: 10.1161/JAHA.122.027736. Epub 2023 Apr 12.
No abstract available

Keywords: hereditary cardiac amyloidosis; metabolomics; prealbumin; random forest classification; restrictive cardiomyopathy; transthyretin.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Amyloid Neuropathies, Familial* / complications
  • Amyloidosis* / metabolism
  • Cardiomyopathies* / metabolism
  • Heart Failure* / complications
  • Heart Failure* / diagnosis
  • Heart Failure* / genetics
  • Humans
  • Machine Learning
  • Mutation
  • Prealbumin / genetics
  • Prealbumin / metabolism

Substances

  • Prealbumin