Sputum IL-6 level as a potential predictor of acute chest syndrome during vaso-occlusive crisis in children with sickle cell disease: Exploratory prospective prognostic accuracy study
1 Department of General Pediatrics and Pediatric Infectious Diseases, Sickle Cell Center, Necker-Enfants malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris Cité, Paris, France.
2 Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutical Implications, Université Paris Cité, Imagine Institute, Inserm U1163, Paris, France.
3 Laboratory of Excellence GR-Ex, Paris, France.
4 Department of Pediatric Intensive care, Necker-Enfants malades Hospital, AP-HP, Université Paris Cité, Paris, France.
5 Centre of Research in Epidemiology and Statistics-CRESS, INSERM, Obstetrical, Perinatal and Pediatric Epidemiology Research Team, Université Paris Cité, Paris, France.
6 Department of Hematology, Necker-Enfants malades Hospital, AP-HP, Université Paris Cité, Paris, France.