A bibliometric analysis of research on R-loop: Landscapes, highlights and trending topics

Ran Li; Bo Liu; Xianglin Yuan; Zuhua Chen

doi:10.1016/j.dnarep.2023.103502

A bibliometric analysis of research on R-loop: Landscapes, highlights and trending topics

DNA Repair (Amst). 2023 Jul:127:103502. doi: 10.1016/j.dnarep.2023.103502. Epub 2023 Apr 14.

Authors

Ran Li¹, Bo Liu¹, Xianglin Yuan², Zuhua Chen³

Affiliations

¹ Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
² Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: [email protected].
³ Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: [email protected].

PMID: 37099848
DOI: 10.1016/j.dnarep.2023.103502

Abstract

R-loop is a necessary intermediate in specific cellular processes. To profile the landscapes, highlights, and trending topics of R-loop, publications related to R-loop from 1976 to 2022 were downloaded and bibliometric analyses were performed by Bibliometrix in R and VOSviewer. 1428 documents (including 1092 articles and 336 reviews) were included. USA, United Kingdom, and China contributed more than one-third of the publications. The annual publication increased rapidly since 2010. The research trend of R-loop has evolved from the discovery of phenomena to the exploration of molecular mechanisms, from the elucidation of biological functions to the analysis of disease correlations. Ongoing roles of R-loop in DNA repair process was highlighted and further analyzed. This study may accelerate R-loop research by highlighting important researches, understanding the trending topic, and integrating with other areas.

Keywords: Bibliometric analysis; DNA repair; Disease; R-loop.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bibliometrics*
DNA Repair
R-Loop Structures*