Developmental Contributions to Obesity: Nutritional Exposures in the First Thousand Days

Gastroenterol Clin North Am. 2023 Jun;52(2):333-345. doi: 10.1016/j.gtc.2023.02.001. Epub 2023 Apr 7.

Abstract

Obesity is prevalent and continuing to rise across all age groups, even children. As obesity is challenging to manage and treat, prevention is critical. Here, we highlight nutritional influences during periods of early developmental plasticity, namely the prenatal period and infancy, that have been shown to contribute to the development of obesity into childhood and beyond. We review recent research that examines maternal nutritional factors including dietary patterns and quality, as well as the infant diet, such as complementary foods and beverages, that influence long-term obesity risk. We end with recommendations for clinicians.

Keywords: Breastfeeding; Diet; Infant; Nutrition; Pregnancy; Sugar-sweetened beverages.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Child
  • Diet / adverse effects
  • Female
  • Food*
  • Humans
  • Infant
  • Obesity*
  • Pregnancy