What are the current trends in G protein-coupled receptor targeted drug discovery?

Vicent Casadó; Verònica Casadó-Anguera

doi:10.1080/17460441.2023.2216014

What are the current trends in G protein-coupled receptor targeted drug discovery?

Expert Opin Drug Discov. 2023 Jul-Dec;18(8):815-820. doi: 10.1080/17460441.2023.2216014. Epub 2023 May 19.

Authors

Vicent Casadó¹, Verònica Casadó-Anguera^{1

2}

Affiliations

¹ Laboratory of Molecular Neuropharmacology, Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Institute of Biomedicine, University of Barcelona, Barcelona, Spain.
² Laboratory of Neuropharmacology-Neurophar, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain.

PMID: 37204339
DOI: 10.1080/17460441.2023.2216014

No abstract available

Keywords: Allosteric drug; G-protein coupled receptor; biased drug; bitopic ligand; bivalent ligand; drug discovery; heteromer-selective drug; orthosteric drug.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Allosteric Regulation
Allosteric Site
Drug Discovery*
Humans
Ligands
Receptors, G-Protein-Coupled*

Substances

Receptors, G-Protein-Coupled
Ligands