Updates on the dermatopathology of pregnancy-associated skin conditions

Fangyi Xie; Shruti Agrawal; Emma F Johnson; Carilyn N Wieland; Dawn Marie R Davis; Regan N Theiler; Julia S Lehman

doi:10.1016/j.humpath.2023.05.005

Updates on the dermatopathology of pregnancy-associated skin conditions

Hum Pathol. 2023 Oct:140:173-195. doi: 10.1016/j.humpath.2023.05.005. Epub 2023 May 18.

Authors

Fangyi Xie¹, Shruti Agrawal², Emma F Johnson², Carilyn N Wieland², Dawn Marie R Davis³, Regan N Theiler⁴, Julia S Lehman⁵

Affiliations

¹ Department of Dermatology, Mayo Clinic, Rochester, MN, 55905, USA.
² Department of Dermatology, Mayo Clinic, Rochester, MN, 55905, USA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.
³ Department of Dermatology, Mayo Clinic, Rochester, MN, 55905, USA; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, 55905, USA.
⁴ Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, 55905, USA.
⁵ Department of Dermatology, Mayo Clinic, Rochester, MN, 55905, USA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA. Electronic address: [email protected].

PMID: 37209919
DOI: 10.1016/j.humpath.2023.05.005

Abstract

Pathologists provide valuable input in the dermatological care of pregnant patients in various contexts. This article provides dermatopathology updates on cutaneous changes associated with pregnancy, organized based on the following classification system: physiological skin changes in pregnancy, specific dermatoses of pregnancy, dermatoses modified in pregnancy, and skin neoplasms in pregnancy. Awareness of the impact of pregnancy on the skin by pathologists is important, as this is an opportunity to contribute to diagnostic precision in this patient population.

Keywords: Atopic eruption of pregnancy; Dermatopathology; Obstetrics; Pemphigoid gestationis; Polymorphic eruption of pregnancy; Pregnancy dermatology; Women's health.