Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma

Oncotarget. 2023 May 26:14:526-527. doi: 10.18632/oncotarget.28441.
No abstract available

Keywords: BRD4; GLI1; SOX2; hedgehog signaling; melanoma.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Cell Cycle Proteins
  • Cell Line, Tumor
  • Cell Proliferation
  • Hedgehog Proteins
  • Humans
  • Melanoma* / drug therapy
  • Nuclear Proteins / metabolism
  • Signal Transduction
  • Transcription Factors*
  • Zinc Finger Protein GLI1 / genetics
  • Zinc Finger Protein GLI1 / metabolism

Substances

  • Transcription Factors
  • Hedgehog Proteins
  • Nuclear Proteins
  • Zinc Finger Protein GLI1
  • BRD4 protein, human
  • Cell Cycle Proteins