Patient-Centric Approaches for Phase I Combination Trials Come on Stage

Alberto Hernando-Calvo; Elena Garralda

doi:10.1158/2159-8290.CD-23-0534

Patient-Centric Approaches for Phase I Combination Trials Come on Stage

Cancer Discov. 2023 Aug 4;13(8):1762-1764. doi: 10.1158/2159-8290.CD-23-0534.

Authors

Alberto Hernando-Calvo^{1

2}, Elena Garralda^{1

2}

Affiliations

¹ Vall d'Hebron University Hospital, Barcelona, Spain.
² Vall d'Hebron Institute of Oncology, Barcelona, Spain.

Abstract

A disruptive clinical trial design allowed Drilon and colleagues to demonstrate proof of concept of the potential of PF-07284892 to overcome resistance mechanisms to targeted therapies in the clinic. See related article by Drilon et al., p. 1789 (7).

Publication types

Editorial
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Humans
Neoplasms* / drug therapy
Oncogenes
Patient-Centered Care