Etripamil Nasal Spray: Therapeutic Potential for Treating Paroxysmal Supraventricular Tachycardia

Am J Cardiovasc Drugs. 2023 Sep;23(5):471-475. doi: 10.1007/s40256-023-00589-2. Epub 2023 Jun 6.

Abstract

Patients with arrythmias are at an increased risk of heart-related comorbidities and complications. Specifically, patients with paroxysmal supraventricular tachycardia (PSVT), a type of arrythmia, are at increased risk of lightheadedness or shortness of breath, due to the increased rate of the heartbeat. Most patients are prescribed oral medications to control their heart rates and maintain a normal heart rhythm. Researchers have been tasked with discovering alternative treatment options with new delivery methods to treat arrythmias such as PSVT. A nasal spray was subsequently designed and is currently undergoing clinical studies. This review aims to present and discuss the current clinical and scientific evidence pertaining to etripamil.

Publication types

  • Review

MeSH terms

  • Humans
  • Nasal Sprays
  • Tachycardia, Paroxysmal* / drug therapy
  • Tachycardia, Supraventricular* / drug therapy
  • Tachycardia, Ventricular*

Substances

  • Nasal Sprays
  • etripamil