Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia

Brennan P Bergeron; Kelly R Barnett; Kashi Raj Bhattarai; Robert J Mobley; Baranda S Hansen; Anthony Brown; Kiran Kodali; Anthony A High; Sima Jeha; Ching-Hon Pui; Junmin Peng; Shondra M Pruett-Miller; Daniel Savic

doi:10.1182/bloodadvances.2022009498

Mutual antagonism between glucocorticoid and canonical Wnt signaling pathways in B-cell acute lymphoblastic leukemia

Blood Adv. 2023 Aug 8;7(15):4107-4111. doi: 10.1182/bloodadvances.2022009498.

Authors

Brennan P Bergeron^{1

2

3}, Kelly R Barnett^{1

2}, Kashi Raj Bhattarai^{1

2}, Robert J Mobley^{1

2}, Baranda S Hansen⁴, Anthony Brown², Kiran Kodali⁵, Anthony A High⁵, Sima Jeha^{1

6}, Ching-Hon Pui^{1

6}, Junmin Peng^{3

5

7

8}, Shondra M Pruett-Miller^{3

4

9}, Daniel Savic^{1

2

3

10}

Affiliations

¹ Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, TN.
² Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN.
³ Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN.
⁴ Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN.
⁵ Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN.
⁶ Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN.
⁷ Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN.
⁸ Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN.
⁹ Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN.
¹⁰ Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN.

No abstract available

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Burkitt Lymphoma*
Glucocorticoids / pharmacology
Glucocorticoids / therapeutic use
Humans
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma* / drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / metabolism
Wnt Signaling Pathway

Substances

Glucocorticoids

Publication types

MeSH terms

Substances

Grants and funding