Long-standing laryngeal rhinoscleroma with rare Mikulicz cells

Raheem Peerani; Manish Shah; Brian Minnema; Hasan Ghaffar; Runjan Chetty; Jan Delabie; Bayardo Perez-Ordonez; Daniel Xia

doi:10.1002/ccr3.7490

Long-standing laryngeal rhinoscleroma with rare Mikulicz cells

Clin Case Rep. 2023 Jun 7;11(6):e7490. doi: 10.1002/ccr3.7490. eCollection 2023 Jun.

Authors

Raheem Peerani^{1

2}, Manish Shah^{1

3}, Brian Minnema¹, Hasan Ghaffar^{2

4}, Runjan Chetty⁵, Jan Delabie^{2

6}, Bayardo Perez-Ordonez^{2

7}, Daniel Xia^{2

6}

Affiliations

¹ North York General Hospital Toronto Ontario Canada.
² Department of Laboratory Medicine and Pathobiology University of Toronto Toronto Ontario Canada.
³ Department of Otolaryngology - Head and Neck Surgery University of Toronto Toronto Ontario Canada.
⁴ Department of Laboratory Medicine St. Michael's Hospital Toronto Ontario Canada.
⁵ Diagnexia Dublin Ireland.
⁶ Division of Hematopathology and Transfusion Medicine University Health Network Toronto Ontario Canada.
⁷ Division of Anatomical Pathology University Health Network Toronto Ontario Canada.

Abstract

Rhinoscleroma is an infectious granulomatous disease. It is important to identify pathognomonic Mikulicz cells on microscopy, as these can be rare and the chronic inflammatory infiltrate can appear otherwise nonspecific on biopsies.

Keywords: Klebsiella ozaenae; Mikulicz cells; ear; infectious disease; nose and throat; rhinoscleroma.

Publication types

Case Reports