SARS-CoV-2-Induced Autoimmune Hepatitis

Cureus. 2023 May 12;15(5):e38932. doi: 10.7759/cureus.38932. eCollection 2023 May.

Abstract

Few case reports discuss the incidences of autoimmune hepatitis (AIH) in patients after SARS-CoV-2 infection. Here, we present a case of SARS-CoV-2-induced AIH in a male patient who came into the emergency department with complaints of weight loss, poor oral intake, nausea, dark-colored urine, clay-colored stools, and scleral icterus, which began two weeks after he tested positive for SARS-CoV-2 PCR. Liver biopsy and subsequent histology confirmed the diagnosis of AIH with the most probable etiology being SARS-CoV-2 infection. The patient was treated with N-acetylcysteine (NAC) and steroids with clinical improvement and eventual discharge home. Our goal is to provide a clinical presentation, treatment, and outcome in a patient with SARS-CoV-2-induced AIH.

Keywords: autoimmune hepatitis; covid; covid-19 and jaundice; gastrointestinal and liver pathology; periportal fibrosis; serology testing.

Publication types

  • Case Reports