Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition

Front Cardiovasc Med. 2023 Jun 8:10:1198204. doi: 10.3389/fcvm.2023.1198204. eCollection 2023.

Abstract

Chronic thromboembolic pulmonary hypertension is a rare but life-threatening complication of long-term central venous catheters (CVC) in children. However, evidence in terms of potential treatment strategies and outcome data remains scarce. We describe two cases of CVC-related thrombosis (Hickman-catheter) complicated by recurrent pulmonary emboli. One patient experienced a complete thromboembolic obstruction of the right pulmonary artery with normal pulmonary pressures and the second patient suffered from a central thromboembolic obstruction of both pulmonary arteries associated with severe pulmonary hypertension. Both patients successfully underwent surgical thromboendarterectomy with deep hypothermic circulatory arrest.

Keywords: chronic thromboembolic pulmonary hypertension; hickmann-catheter; parenteral nutrition (PN); pulmonary embolism; pulmonary endarterectomy.

Publication types

  • Case Reports