Primary Effusion Lymphoma, Multicentric Castleman's Disease, and Kaposi's Sarcoma in an HHV-8 and HIV-Positive Patient: A Case Report

Medicina (Kaunas). 2023 May 30;59(6):1049. doi: 10.3390/medicina59061049.

Abstract

Primary effusion lymphoma (PEL), Kaposi's sarcoma (KS), and multicentric Castleman's disease (MCD) is an uncommon group of diseases included in the same spectrum with related characteristics. The coexistence of all of them in the same individual is a rare occurrence. We present the case of a 25-year-old patient diagnosed with human immunodeficiency virus (HIV) and the development of all these related pathologies. Despite the use of intensive treatment according to the latest recommendations, the evolution was unfavorable. This case reflects the need for new therapies and research in this field.

Keywords: HIV; PEL; lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Castleman Disease
  • HIV Infections* / complications
  • Herpesvirus 8, Human*
  • Humans
  • Lymphoma, Primary Effusion* / complications
  • Lymphoma, Primary Effusion* / diagnosis
  • Sarcoma, Kaposi* / complications
  • Sarcoma, Kaposi* / pathology

Supplementary concepts

  • Multi-centric Castleman's Disease

Grants and funding

This research received no external funding.