Exposure to Phosphates and Nitrites through Meat Products: Estimation of the Potential Risk to Pregnant Women

Nutrients. 2023 Jun 16;15(12):2777. doi: 10.3390/nu15122777.

Abstract

Diet during pregnancy is one of the most important nutritional challenges associated with some risks for the mother and the fetus. For the first time, the study aims to estimate long-term (2018-2022) exposure to nitrate and phosphates in Serbian pregnant women, based on individual consumption data and accurate values measured in frequently consumed meat products. For this purpose, seven types of meat products, consisting of 3047 and 1943 samples, were collected from retail markets across Serbia, to analyze nitrites and phosphorus content, respectively. These data were combined with meat product consumption data from the Serbian National Food Consumption Survey to assess dietary intake of nitrites and phosphate. The results were compared with the acceptable daily intake (ADI) proposed by the European Food Safety Authority. The average dietary exposure (EDI) to phosphorus ranged from 0.733 mg/kg bw/day (liver sausage and pate) to 2.441 mg/kg bw/day (finely minced cooked sausages). Considering nitrite intake, the major sources were bacon (0.030 mg/kg bw/day) and coarsely minced cooked sausages (0.0189 mg/kg bw/day). In our study, average nitrite and phosphorus exposure in the Serbian pregnant women population are far below the EFSA recommendations (ADI 0.07 mg/kg bw/day and 40 mg/kg bw/day, respectively).

Keywords: exposure assessment; food additives; meat products; nitrites; phosphates; pregnant women.

MeSH terms

  • Diet
  • Female
  • Humans
  • Meat / analysis
  • Meat Products* / analysis
  • Nitrites*
  • Phosphates
  • Phosphorus
  • Pregnancy
  • Pregnant Women

Substances

  • Nitrites
  • Phosphates
  • Phosphorus

Grants and funding

This study was supported by the Ministry of Science, Technological Development and Innovation, Republic of Serbia, Grant No. 451-03-47/2023-01/200050 and 451-03-47/2023-01/200015 from 03.02.2023.