Vicious Twins: RyR2 Dysfunction and Structural Remodeling

Niels Voigt; Fitzwilliam Seibertz; Funsho E Fakuade

doi:10.1161/CIRCRESAHA.123.323144

Vicious Twins: RyR2 Dysfunction and Structural Remodeling

Circ Res. 2023 Jul 7;133(2):193-195. doi: 10.1161/CIRCRESAHA.123.323144. Epub 2023 Jul 6.

Authors

Niels Voigt^{1

2

3}, Fitzwilliam Seibertz^{1

2

3}, Funsho E Fakuade^{1

2

3}

Affiliations

¹ Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Georg August University Göttingen, Germany (N.V., F.S., F.E.F.).
² DZHK (German Center for Cardiovascular Research), partner site Göttingen, Germany (N.V., F.S., F.E.F.).
³ Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, Germany (N.V., F.S., F.E.F.).

PMID: 37410856
DOI: 10.1161/CIRCRESAHA.123.323144

No abstract available

Keywords: Editorial; arrhythmias, cardiac; atrial fibrillation; calcium; calcium-calmodulin-dependent protein kinase type 2; cardiomyopathies; ion channels.

Publication types

Editorial
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Calcium / metabolism
Calcium Signaling
Calcium-Calmodulin-Dependent Protein Kinase Type 2 / metabolism
Myocytes, Cardiac* / metabolism
Ryanodine Receptor Calcium Release Channel* / genetics
Ryanodine Receptor Calcium Release Channel* / metabolism
Sarcoplasmic Reticulum / metabolism

Substances

Ryanodine Receptor Calcium Release Channel
Calcium
Calcium-Calmodulin-Dependent Protein Kinase Type 2