Rapid Colorimetric and Fluorometric Discrimination of Maleic Acid vs. Fumaric Acid and Detection of Maleic Acid in Food Additives

J Fluoresc. 2024 May;34(3):1015-1024. doi: 10.1007/s10895-023-03330-z. Epub 2023 Jul 13.

Abstract

An anthracene thiazole based Schiff base L was synthesized and employed for fluorescence switch-on detection of maleic acid in aqueous DMSO. The non-fluorescent L (10-5 M) showed an instantaneous and selective fluorescence enhancement at 506 nm upon interaction with maleic acid (10-5 M). Other potential carboxylic acids (10-5 M), such as malic acid, citric acid, acetic acid, cinnamic acid, tartaric acid, succinic acid, fumaric acid, oxalic acid and malonic acid failed to alter the chromo-fluorogenic properties of L. Probe L can be employed to detect maleic acid down to 2.74 × 10-6 M. The probe L showed good linearity from 2.97 to 6.87 µM. Analytical utility of L was examined by detecting maleic acid in various food additives and drosophila larvae.

Keywords: Color change; DFT; Fluorescence probe; Maleic acid; Schiff base.

MeSH terms

  • Animals
  • Colorimetry* / methods
  • Fluorometry* / methods
  • Food Additives* / analysis
  • Fumarates* / analysis
  • Fumarates* / chemistry
  • Maleates* / chemistry
  • Molecular Structure

Substances

  • maleic acid
  • fumaric acid
  • Maleates
  • Fumarates
  • Food Additives