The temporal relationship of alcohol use and subsequent self-reported health status among people with HIV

Jarratt D Pytell; Ximin Li; Carol Thompson; Catherine R Lesko; Mary E McCaul; Heidi Hutton; D Scott Batey; Edward Cachay; Kenneth H Mayer; Sonia Napravnik; Katerina Christopoulos; Cui Yang; Heidi M Crane; Geetanjali Chander; Bryan Lau

doi:10.1016/j.ajmo.2022.100020

The temporal relationship of alcohol use and subsequent self-reported health status among people with HIV

Am J Med Open. 2023 Jun:9:100020. doi: 10.1016/j.ajmo.2022.100020. Epub 2022 Jun 28.

Authors

Jarratt D Pytell¹, Ximin Li², Carol Thompson², Catherine R Lesko³, Mary E McCaul⁴, Heidi Hutton⁴, D Scott Batey⁵, Edward Cachay⁶, Kenneth H Mayer⁷, Sonia Napravnik^{8

9}, Katerina Christopoulos¹⁰, Cui Yang¹¹, Heidi M Crane¹², Geetanjali Chander^{1

2}, Bryan Lau^{1

2}

Affiliations

¹ Department of Medicine, Johns Hopkins School of Medicine, 5200 Eastern Avenue, Baltimore, MD 21224, USA.
² Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
³ Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
⁴ Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, MD, USA.
⁵ Department of Social Work, University of Alabama at Birmingham, Birmingham, AL, USA.
⁶ Department of Medicine, University of California, San Diego, CA, USA.
⁷ Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
⁸ Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
⁹ Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
¹⁰ Department of Medicine, Zuckerberg San Francisco General Hospital, University of California San Francisco, San Francisco, CA, USA.
¹¹ Department of Health, Behavior, and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
¹² Department of Medicine, UW School of Medicine, University of Washington, Seattle, WA, USA.

Abstract

Background: Alcohol use among people with HIV is associated with worse HIV treatment outcomes. Its impact on self-reported health status is unclear.

Setting: Longitudinal cohort of people with HIV engaged in care across 7 clinics participating in the Centers for AIDS Research Network of Integrated Care Systems between January 2011 and June 2014.

Methods: A total of 5046 participants were studied. A quantile regression model estimated the association of alcohol use levels with subsequent self-reported health status score, accounting for multiple covariates including depressive symptoms. Women, men who have sex with women, and men who have sex with men were analyzed separately.

Results: Prevalence of heavy alcohol use was 21%, 31%, and 37% among women, men who have sex with women, and men who have sex with men, respectively. Women with heavy alcohol use had a subsequently decreased median self-reported health status score compared to women with no or moderate alcohol use (odds ratio [OR]: 0.76; 95% confidence interval [CI]: 0.58-0.99); this association was not explained by the presence of depressive symptoms. There was no observed association of alcohol use level on subsequent self-reported health status among men who have sex with women. Men who have sex with men reporting no alcohol use had a subsequently decreased median self-reported health status compared to moderate alcohol use (OR: 0.88; 95% CI: 0.80-0.97).

Conclusion: Heavy alcohol use is associated with worsened self-reported health status at subsequent visits among women with HIV and not men with HIV.

Keywords: Alcohol; HIV; Quality of life; Self-reported health status.

Abstract

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