High perilesional T2-FLAIR signal around anterior temporal perivascular spaces: How can fluid suppressed Amide Proton Transfer weighted imaging further comfort the diagnosis

Darío Herrán de la Gala; Stefano Casagranda; Bertrand Mathon; Emmanuel Mandonnet; Lucia Nichelli

doi:10.1016/j.mri.2023.07.011

High perilesional T2-FLAIR signal around anterior temporal perivascular spaces: How can fluid suppressed Amide Proton Transfer weighted imaging further comfort the diagnosis

Magn Reson Imaging. 2023 Nov:103:119-123. doi: 10.1016/j.mri.2023.07.011. Epub 2023 Jul 20.

Authors

Darío Herrán de la Gala¹, Stefano Casagranda², Bertrand Mathon³, Emmanuel Mandonnet⁴, Lucia Nichelli⁵

Affiliations

¹ Department of Radiology, «Marqués de Valdecilla» University Hospital, Santander, Spain. Electronic address: [email protected].
² Department of Research & Development Advanced Applications, Olea Medical, Avenue des Sorbiers, La Ciotat, France.
³ Department of Neurosurgery, Pitié-Salpêtrière University Hospital, AP-HP, Paris, France.
⁴ Department of Neurosurgery, Lariboisière University Hospital, AP-HP, Paris, France.
⁵ Department of Radiology, Pitié-Salpêtrière University Hospital, AP-HP, Paris, France.

PMID: 37481093
DOI: 10.1016/j.mri.2023.07.011

Abstract

Areas of marked T2-FLAIR hyperintensity around perivascular spaces can be misdiagnosed as tumor, especially in case of lesion evolution. In this report, we show and describe increased T2-FLAIR signal intensity around anterior temporal perivascular spaces in three patients and shortly review this poorly known entity. In addition, we discuss for the first time the added value of fluid suppressed APTw imaging, an emerging noninvasive molecular technique, in the characterization of this "do not touch" abnormality.

Keywords: Amide; MRI; Perivascular spaces; Proton.

Publication types

Case Reports

MeSH terms

Humans
Magnetic Resonance Imaging* / methods
Protons*

Substances

Protons