The evolving landscape of salivary gland tumors

CA Cancer J Clin. 2023 Nov-Dec;73(6):597-619. doi: 10.3322/caac.21807. Epub 2023 Jul 25.

Abstract

Salivary gland cancers are a rare, histologically diverse group of tumors. They range from indolent to aggressive and can cause significant morbidity and mortality. Surgical resection remains the mainstay of treatment, but radiation and systemic therapy are also critical parts of the care paradigm. Given the rarity and heterogeneity of these cancers, they are best managed in a multidisciplinary program. In this review, the authors highlight standards of care as well as exciting new research for salivary gland cancers that will strive for better patient outcomes.

Keywords: cancer; head and neck; multimodality; salivary gland carcinoma; targeted therapy.

Publication types

  • Review

MeSH terms

  • Humans
  • Salivary Gland Neoplasms* / diagnosis
  • Salivary Gland Neoplasms* / therapy