Correlates of increased risk for alcoholism in young men

Prog Neuropsychopharmacol Biol Psychiatry. 1986;10(2):211-8. doi: 10.1016/0278-5846(86)90075-8.

Abstract

Healthy men, aged 21-28, were divided into two groups according to the DSM-III diagnosis of alcoholism in their biological fathers. Evoked potentials from each subject were measured according to a visual odd-ball paradigm designed to elicit large responses in the midline parietal, Pz, lead. Subjects with alcoholic fathers produced significantly smaller amplitudes of the P3 component compared to subjects with non-alcoholic fathers. Reaction time, task difficulty and subject drinking history did not distinguish the groups. Subject's drinking history was not related to P3 amplitude.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Alcohol Drinking
  • Alcoholism / epidemiology*
  • Alcoholism / physiopathology
  • Evoked Potentials, Visual*
  • Humans
  • Male
  • Nervous System / physiopathology*
  • Reaction Time / physiology
  • Risk