Sickle cell disease: Contributing factors and radiological assessments

Gail Cherry-Peppers; Cheryl Fryer; Andrea D Jackson; Xinbin Gu; Debra Ford; Alison Glascoe; Dawn Smith; Meirong Liu; Jacquelyn Dunmore-Griffith; Gillian Robinson-Warner; Crystal McIntosh; Jezelle Sonnier; Lisa Slade; Adel Rizkalla; Shakeya Mundey; Nyree Dawson; Manouchka Fleurinord; Baron Edmonson; Courtney Ford; Jillian Griffith; Gretchen Peppers; Kavya Muttanahally; Fatima Mncube-Barnes; Terri Watkins-Bryant

doi:10.1016/j.jnma.2023.05.004

Sickle cell disease: Contributing factors and radiological assessments

J Natl Med Assoc. 2024 Dec;116(6):636-641. doi: 10.1016/j.jnma.2023.05.004. Epub 2023 Jul 24.

Authors

Gail Cherry-Peppers¹, Cheryl Fryer², Andrea D Jackson³, Xinbin Gu⁴, Debra Ford⁵, Alison Glascoe⁶, Dawn Smith⁷, Meirong Liu⁸, Jacquelyn Dunmore-Griffith⁹, Gillian Robinson-Warner¹⁰, Crystal McIntosh¹¹, Jezelle Sonnier¹², Lisa Slade¹³, Adel Rizkalla¹⁴, Shakeya Mundey¹⁵, Nyree Dawson¹⁶, Manouchka Fleurinord¹⁷, Baron Edmonson¹⁸, Courtney Ford¹⁹, Jillian Griffith²⁰, Gretchen Peppers²¹, Kavya Muttanahally²², Fatima Mncube-Barnes²³, Terri Watkins-Bryant²⁴

Affiliations

¹ Associate Professor, Director Oral Diagnosis and Radiology, Howard University College of Dentistry, Howard University College of Dentistry. Electronic address: [email protected].
² Associate Dean Academic Affairs, Howard University College of Dentistry. Electronic address: [email protected].
³ Dean, Howard University College of Dentistry, Washington, DC. Electronic address: [email protected].
⁴ Associate Dean for Research, Chair, Research Committee, Howard University College of Dentistry. Electronic address: [email protected].
⁵ Senior Associate Dean for Academic Affairs, Howard University College of Medicine. Electronic address: [email protected].
⁶ Comprehensive Care, Chair, Howard University College of Dentistry. Electronic address: [email protected].
⁷ Chair, Department of Dental Hygiene, Howard University College of Dentistry. Electronic address: [email protected].
⁸ Howard University School of Social Work. Electronic address: [email protected].
⁹ Department of Radiation Oncology, Howard University College of Medicine. Electronic address: [email protected].
¹⁰ Assistant Professor, Department of Restorative Dentistry, Howard University College of Dentistry. Electronic address: [email protected].
¹¹ Associate Professor, Chair, Department of Periodontics, Howard University College of Dentistry. Electronic address: [email protected].
¹² Assistant Professor, Department of Restorative Dentistry, Howard University College of Dentistry. Electronic address: [email protected].
¹³ Director, Department of Endodontics, Howard University College of Dentistry. Electronic address: [email protected].
¹⁴ Assistant Professor, Department of Restorative Dentistry, Howard University College of Dentistry. Electronic address: [email protected].
¹⁵ Assistant Professor, Comprehensive Care, Howard University College of Dentistry, Washington, DC. Electronic address: [email protected].
¹⁶ Assistant Professor, Department of Dental Hygiene, Howard University College of Dentistry. Electronic address: [email protected].
¹⁷ Research Student Committee, Howard University College of Dentistry, Ashleigh Bellamy Research Student Committee, Howard University College of Dentistry. Electronic address: [email protected].
¹⁸ Research Student Committee, Howard University College of Dentistry. Electronic address: [email protected].
¹⁹ Summer Research Project, Howard University College of Dentistry. Electronic address: [email protected].
²⁰ Summer Research Project, Howard University College of Dentistry. Electronic address: [email protected].
²¹ Research Committee Coordinator, Howard University College of Dentistry. Electronic address: [email protected].
²² Research Summer Project, Howard University College of Dentistry. Electronic address: [email protected].
²³ Research Committee, Howard University College of Dentistry. Electronic address: [email protected].
²⁴ Research Committee, Howard University College of Dentistry. Electronic address: [email protected].

PMID: 37495445
DOI: 10.1016/j.jnma.2023.05.004

Abstract

Sickle Cell Disease (SCD) is genetically described as an autosomal blood disorder resulting from the presence of a mutated form of hemoglobin. Morbidity, frequency of crisis, degree of anemia, and organ systems involved vary considerably per patient. Dental health professionals and other specialists commonly request comprehensive medical consultations prior to performing complex periodontal, endodontic, and surgical procedures. In order to have successful dental outcomes and minimize posttreatment dental complications, relevant disease indicators are noted. This review is to raise awareness of the impact of oral diseases in patients with sickle cell disease and to emphasize the importance of full medical disclosure, radiographic interpretation, and a well-documented medical history, and a well-written consultation which can guide treatment planning and greatly improve the course of dental treatment.

Keywords: Consultation; Mandible changes; Pain; Radiographic findings; Sickle cell.

Publication types

Review

MeSH terms

Anemia, Sickle Cell* / complications
Humans
Radiography