K2CO3-Promoted oxy-Michael Addition/Cyclization of α, β-Unsaturated Carbonyl Compounds with Naphthols: Synthesis of Naphthopyrans

Molecules. 2023 Jul 19;28(14):5502. doi: 10.3390/molecules28145502.

Abstract

A potassium carbonate promoted tandem oxy-Michael addition/cyclization of α,β-unsaturated carbonyl compounds with naphthol derivatives for the synthesis of 2-substituted naphthopyrans was developed. Using the readily available, inexpensive potassium carbonate as the promoter, a range of different substituted naphthopyrans were prepared.

Keywords: naphthopyrans; potassium carbonate; synthesis; tandem oxy-Michael addition/cyclization.