The COVID-19 Pandemic and Coronary Heart Disease: the Next Surge

Curr Atheroscler Rep. 2023 Sep;25(9):559-569. doi: 10.1007/s11883-023-01131-0. Epub 2023 Aug 2.

Abstract

Purpose of review: In this narrative review, we highlight different ways in which the COVID-19 pandemic has impacted coronary heart disease (CHD) burden and how a surge in morbidity and mortality may be expected in the near future. We also discuss potential solutions, and the direction subsequent research and corrective actions should take.

Recent findings: COVID-19 has been implicated in the development and worsening of CHD via acute and chronic mechanisms in the form of plaque rupture, destabilization, and sustenance of a chronic inflammatory state leading to long COVID syndrome and increased rates of myocardial infarction. However, indirectly the pandemic is likely to further escalate the CHD burden through poor health behaviors such as tobacco consumption, reduced physical activity, economic devastation and its associated sequelae, and regular cardiac care interruptions and delays. COVID-19 has increased the total CHD burden and will require extensive resource allocation and multifaceted strategies to curb future rise.

Keywords: COVID-19; Coronary heart disease; Economic; Myocardial infarction; Non-communicable diseases; Pandemic.

Publication types

  • Review
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • COVID-19*
  • Coronary Disease* / epidemiology
  • Humans
  • Myocardial Infarction* / epidemiology
  • Pandemics
  • Post-Acute COVID-19 Syndrome