Autophagy in intestinal epithelial cells prevents gut inflammation

Shahar Telpaz; Shai Bel

doi:10.1016/j.tcb.2023.07.010

Autophagy in intestinal epithelial cells prevents gut inflammation

Trends Cell Biol. 2023 Oct;33(10):817-819. doi: 10.1016/j.tcb.2023.07.010. Epub 2023 Aug 14.

Authors

Shahar Telpaz¹, Shai Bel²

Affiliations

¹ Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
² Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel. Electronic address: [email protected].

PMID: 37586983
DOI: 10.1016/j.tcb.2023.07.010

Abstract

Intestinal epithelial cells form the largest barrier in the body, separating us from the outside world. Here, we review recent findings that highlight the role of autophagy in the cell-intrinsic response of the epithelial cells to the harsh intestinal environment and how they shape host physiology.

Keywords: autophagy; epithelium; inflammation; inflammatory bowel diseases; intestinal barrier; intestine.

Publication types

Review

MeSH terms

Autophagy*
Epithelial Cells*
Humans
Inflammation